What condition involves the overproduction of parathyroid hormone, leading to increased calcium dissolution?

What condition involves the overproduction of parathyroid hormone, leading to increased calcium dissolution?

• A. Hyperthyroidism
• B. Hypoparathyroidism
• C. Hyperparathyroidism
• D. Osteoporosis

Answer: (C)

The condition that involves the overproduction of parathyroid hormone is hyperparathyroidism. In this disorder, the parathyroid glands, which are responsible for regulating calcium levels in the body, become overactive and secrete excessive amounts of parathyroid hormone (PTH). This overproduction of PTH leads to increased osteoclastic activity, which is the process by which bone is broken down, resulting in the release of calcium into the bloodstream. As a consequence, hyperparathyroidism often results in elevated serum calcium levels (hypercalcemia) and can lead to a range of symptoms, including kidney stones, bone pain, and digestive issues. The increased calcium dissolution from bones can contribute to weakened bone structure, though it is distinct from conditions like osteoporosis, which is primarily characterized by low bone density and increased fracture risk. Understanding hyperparathyroidism is crucial in the context of bone health, as it emphasizes the role of hormonal regulation in maintaining calcium balance and skeletal integrity.

The condition that involves the overproduction of parathyroid hormone is hyperparathyroidism. In this disorder, the parathyroid glands, which are responsible for regulating calcium levels in the body, become overactive and secrete excessive amounts of parathyroid hormone (PTH). This overproduction of PTH leads to increased osteoclastic activity, which is the process by which bone is broken down, resulting in the release of calcium into the bloodstream.

As a consequence, hyperparathyroidism often results in elevated serum calcium levels (hypercalcemia) and can lead to a range of symptoms, including kidney stones, bone pain, and digestive issues. The increased calcium dissolution from bones can contribute to weakened bone structure, though it is distinct from conditions like osteoporosis, which is primarily characterized by low bone density and increased fracture risk.

Understanding hyperparathyroidism is crucial in the context of bone health, as it emphasizes the role of hormonal regulation in maintaining calcium balance and skeletal integrity.