What role does Insulin-Like Growth Factor (IGF-1) play in bone health?

What role does Insulin-Like Growth Factor (IGF-1) play in bone health?

• A. It decreases skeletal growth
• B. It has no effect on bone
• C. It is essential for growth and stimulates bone cells
• D. It prevents bone resorption

Answer: (C)

Insulin-Like Growth Factor 1 (IGF-1) plays a crucial role in bone health primarily through its involvement in the regulation of growth and development of bone tissue. It is produced mainly in the liver and is stimulated by growth hormone. IGF-1 promotes the proliferation and activity of osteoblasts, which are the bone-forming cells. This stimulation is essential for bone growth and mineralization, contributing to the overall density and strength of the bone. Additionally, IGF-1 aids in the maintenance of skeletal integrity by influencing the activity of other hormones and growth factors involved in bone remodeling. Its anabolic effects help in the formation of new bone tissue and can counteract the effects of bone resorption if balanced appropriately. The other options do not accurately reflect the functions of IGF-1 in bone health; thus, they do not capture the complete significance of IGF-1 in stimulating bone cells and supporting skeletal growth.

Insulin-Like Growth Factor 1 (IGF-1) plays a crucial role in bone health primarily through its involvement in the regulation of growth and development of bone tissue. It is produced mainly in the liver and is stimulated by growth hormone. IGF-1 promotes the proliferation and activity of osteoblasts, which are the bone-forming cells. This stimulation is essential for bone growth and mineralization, contributing to the overall density and strength of the bone.

Additionally, IGF-1 aids in the maintenance of skeletal integrity by influencing the activity of other hormones and growth factors involved in bone remodeling. Its anabolic effects help in the formation of new bone tissue and can counteract the effects of bone resorption if balanced appropriately.

The other options do not accurately reflect the functions of IGF-1 in bone health; thus, they do not capture the complete significance of IGF-1 in stimulating bone cells and supporting skeletal growth.